Vitamin E TPGS

Abstract Poor aqueous solubility and thereby poor and/or variable bioavailability of drug candidates is frequently overcome by developing enabling formulations...

Abstract A d-α-Tocopheryl Polyethylene Glycol-1000 Succinate (TPGS)-functionalized nanoparticle formulation was developed for the co-delivery of Paclitaxel (PTX) and Gefitinib (GEF)...

Abstract Topical dosage forms represent a critical segment of pharmaceutical products, offering localized drug delivery with minimal systemic exposure. This...

PMC Isochem, have developed four Vitamin E TPGS premixes ( see the brochure below) with 4 common excipients used as...

Abstract Oral administration of proteins and peptides is extremely difficult due to the nature of the digestive system, which is...

Abstract Uveitis is an ocular inflammatory condition that can be infectious or non-infectious, affecting various ocular structures. Corticosteroids and immunomodulators...

Abstract Ketoconazole (KTZ) functions by suppressing the propagation of ergosterol, an essential element of the fungal cell membrane. However, its...

Abstract Polyethoxylated (PEO)-based nonionic surfactants, such as D-α-Tocopheryl polyethylene glycol succinate (TPGS), offer significant advantages in drug delivery due to...

Abstract Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer lacking estrogen receptors, progesterone receptors, and HER2 expression,...

Abstract Aim Proteolysis targeting chimeras (PROTACs) exhibit a unique and promising pharmacology. However, this comes with molecular properties exceeding the...