STYL'One Evo R&D - Scale-Up and Production Support

STYL’ONE EVO TABLETING INSTRUMENT

The all-in-one multi-functional R&D press from early API characterization and formulation to scale-up at production speed

The most advanced R&D press designed as multifunction tool adapted to every demanding need from early research to production support

A REAL SWISS ARMY KNIFE FOR THE MOST DEMANDING SCIENTIST

POWERFUL, YET EASY TO USE
From the beginning the STYL’One Evo has been designed as an easy to use, easy to clean R&D press. All parts are easy to dismantle to go in a dishwasher and maintenance is simplified with no pollution risks from hydraulic fluids.

The power full software is very intuitive and changing format takes a few minutes, allowing to set-up studies very efficiently. Flexibility include working in displacement mode like any rotary press or working with given compression force targets to answer formulators’ needs.

You can create your own experiment, use saw tooth or square profile, or replicate rotary press or roll compactors
behavior. A unique versatility in a tableting equipment that can also meet GMP requirements for small production batches.

Open your research horizon with STYL’One Evo now!

FULLY INSTRUMENTED PRESS FOR EARLY API CHARACTERIZATION
The STYL’One Evo comes fully equipped to provide you precise information on your powder. Additional accessories enable you to measure die-wall, heat, take-off, etc .

STYL’One Evo compaction simulator for R&D, scale-up and production support

AUTOMATED RESEARCH FOR QUICK FORMULATION SCREENING
The automation allows you to automatically produce tablets at a given target force, and to plot a pressure/tensile strength graph in no time.

SINGLE LAYER, UPGRADABLE TO MULTILAYER AND TAB IN TAB
There are no limits should you wish to explore those avenues. Simple software and hardware guidance allows you to set-up weight and tamping force of your 5 layer tablets in a few minutes with no powder loss.

Multilayer tableting, Easy format change

PRODUCTION PRESS MIMICKING FOR SCALE-UP AND TROUBLESHOOTING
The STYL’One Evo is a compaction simulator that can reproduce the high compression speed of large production rotary presses, allowing you to produce a small batch of real prototypes of your production. The paddle feed shoe and weight regulation system help you in supporting your production floor in problem solving.

ROLL COMPACTION SIMULATION
The unique hybrid modelling optional package can represent any roll compactor.

By setting the target solid fraction of “riblets” = “ribbon tablets”, the formulator can validate his options in dry granulation, and predefine the set-up parameter of his roll compactor (gap, speed, compaction pressure).

STANDARD, MULTI-TIPS AND OVERSIZED TOOLINGS
The STYL’One Evo can be fitted with EURO/TSM B&D tooling but also reinforced head D-441, multi tips for mini-tabs, or even very large sizes for dishwasher tablets.

Configure your tableting equipment with options adapted to your needs

EARLY RESEARCH AND DEVELOPMENT OPTIONS
You can instrument your die wall, adapt heat/cooling systems, use specific feed shoe, instrument take-off. The tab in tab feed shoe allows you to produce a batch of similar core tablets to test impact on bioavailability sdf

WE NOT ONLY PROVIDE YOU THE MOST ADVANCED EQUIPMENT, BUT
OUR FORMULATION SCIENTISTS TEACH YOU HOW TO GET THE MOST OF IT

SCALE-UP AND PRODUCTION SUPPORT
Optional GMP software brings your production to new levels with weight regulation and tablet rejection system. The micro dosing unit allows production using external lubrication. The software enables automatic data transfer from hardness or 5-parameter tablet testers.

ALL LEVELS OF CONTAINMENT POSSIBLE
By design the STYL’One Evo is very clean to lower the risk of exposure. Standard equipment uses only limited amount of powder, and the vacuum creates negative pressure in the compression zone. Additional Enhanced Operator Safety allows you to control and monitor this negative pressure or flood your equipment with Nitrogen. Full containment can be extended to an eight-glove station built around the tableting instrument. The tablets are being produced and can be checked before exiting the isolator.

Technical Data

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See the full technical brochure on “STYL’One Evo R&D” here

(click the picture to download the brochure)

Source: MEDELPHARM technical brochure “STYL’One Evo R&D”

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