Recent developments in improving the emulsifying properties of chitosan

6. April 2023

Chitosan is one of the valuable products obtained from crustacean waste. The unique characteristics of chitosan (antimicrobial, antioxidant, anticancer, and...

The development of a solid lipid nanoparticle (SLN)-based lacticin 3147 hydrogel for the treatment of wound infections

1. April 2023

Chronic wounds affect millions of people globally. This number is set to rise with the increasing incidence of antimicrobial-resistant bacterial...

Injectable Chitosan-Based Hydrogels for Trans-Cinnamaldehyde Delivery in the Treatment of Diabetic Foot Ulcer Infections

31. March 2023

Diabetic foot ulcers (DFU) are among the most common complications in diabetic patients and affect 6.8% of people worldwide. Challenges...

Levofloxacin in nanostructured lipid carriers: Preformulation and critical process parameters for a highly incorporated formulation

20. September 2022

The first step of a successful nanoformulation development is preformulation studies, in which the best excipients, drug-excipient compatibility and interactions...

graphical abstract of Controlled and Local Delivery of Antibiotics by 3D CoreShell Printed Hydrogel Scaffolds to Treat Soft Tissue Infections

Controlled and Local Delivery of Antibiotics by 3D Core/Shell Printed Hydrogel Scaffolds to Treat Soft Tissue Infections

17. December 2021

Soft tissue infections in open fractures or burns are major cause for high morbidity in trauma patients. Sustained, long-term and...

Machine Learning Predicts Drug Metabolism and Bioaccumulation by Intestinal Microbiota

25. November 2021

Over 150 drugs are currently recognised as being susceptible to metabolism or bioaccumulation (together described as depletion) by gastrointestinal microorganisms;...

The rheological properties of the calcium hydroxide paste formulations: chlorhexidine-free calcium hydroxide paste (CH) and calcium hydroxide with 1% chlorhexidine (CHX) (10 × 103 mg/L): (a) frequency sweeps: determining G′ and G″ at a constant strain of 0.01%; (b) amplitude sweeps: determining G′ and G″ at a different shear strain; (c) time sweeps: evolution of the storage (G′) and loss (G″) moduli as a function of time at a frequency of 2.5 rad/s at 20 °C; (d) viscosity: shear-thinning evaluation by shear-rate dependent variations in viscosity.

How Adding Chlorhexidine or Metallic Nanoparticles Affects the Antimicrobial Performance of Calcium Hydroxide Paste as an Intracanal Medication: An In Vitro Study

12. November 2021

The aim of our study was to explore the potential value of metallic (Ag, Cu, and Zn) salts, polymer/metallic nanoparticles,...

antimicrobial