Bioavailability enhancement

Abstract Solid eutectic mixtures of self-dispersible polyethylene glycol-40-stearate with fenofibrate or ibuprofen—prepared by casting or by twin-screw extrusion—were compared in...

Abstract The administration of veterinary medicines via drinking water or feed ingredients is a widely adopted method in intensive livestock and poultry...

Abstract Aim Proteolysis targeting chimeras (PROTACs) exhibit a unique and promising pharmacology. However, this comes with molecular properties exceeding the...

Abstract Chlorothiazide (CTZ), a widely used thiazide diuretic, exhibits poor and variable oral bioavailability due to site-specific absorption and carrier-mediated...

Abstract Diabetes mellitus (DM) poses a significant global health challenge, with escalating prevalence rates and associated complications necessitating urgent attention....

Abstract Background: D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS), an amphiphilic derivative of natural vitamin E, functions as both a drug efflux...

Abstract Injectable hydrogels play a crucial role in various biomedical applications, serving as fillers in tissue engineering, facilitating cell repair,...

Abstract Introduction Avanafil (AVA) is a very efficient phosphodiesterase type 5 inhibitor for the treatment of erectile dysfunction. However, it...

Abstract Clofazimine (CFZ) is a highly effective antibiotic against leprosy and drug-resistant tuberculosis and is on the WHO List of...

Abstract Ternary co-amorphous systems, comprising a drug, a low molecular weight co-former, and a polymer, are a promising approach to...