Investigating the Use of Polymeric Binders in Twin Screw Melt Granulation Process for Improving Compactibility of Drugs

4. September 2016

Traditionally, the melt granulation for pharmaceutical products was performed at low temperature (<90°C) with high-shear granulators using low-melting waxy binders,...

Improving the granule strength of roller-compacted ibuprofen sodium for hot-melt coating processing

25. June 2016

25. June 2016 Abstract Solvent-free hot-melt coating processing is a novel and cost-efficient approach to manufacturing taste-masked multiparticulate systems. However,...

Once-daily amoxicillin immediate- and extended-release bilayer tablets

25. June 2016

Multilayer/bilayer tablets have been applied for the formulation of incompatible components for compound preparations, but more often they are used...

Comparative Study Between Different Ready-Made Orally Disintegrating Platforms for the Formulation of Sumatriptan Succinate Sublingual Tablets

9. April 2016

09. April 2016 Sumatriptan succinate (SS) is a selective serotonin receptor agonist used for the treatment of migraine attacks, suffering...

Rapid-Onset Sildenafil Sublingual Drug Delivery Systems: In Vitro Evaluation and In Vivo Pharmacokinetic Studies in Rabbits

21. March 2016

21. March 2016 The aim of the present study was to prepare sublingual delivery systems for sildenafil and evaluate its...

Novel tablet formulation of amorphous indomethacin using wet granulation with a high-speed mixer granulator combined with porous calcium silicate

13. March 2016

13. March 2016 Solid dispersion techniques are useful for improving the dissolution of poorly water-soluble drugs. This study aimed...

Bioavailability enhancement