Bioavailability enhancement

Abstract In the present study, we aimed to prepare a gastroretentive drug delivery system that would be both highly resistant...

Abstract It is often challenging to precisely manipulate the release behavior of hydrophilic drugs that is believed to be crucial...

03. January 2017 Abstract Efavirenz (EFV), a non-nucleoside reverse transcriptase inhibitor (NNRTI), is part of first-line therapy for the treatment...

27. December 2016 Abstract Purpose: To design controlled release ketorolac tromethamol (KT) matrix tablets for increased drug bioavailability. Methods: Waxes...

15. December 2016 Abstract Solid dispersion formulations made of itraconazole (ITZ) and Soluplus® (polyethylene glycol, polyvinyl acetate and polyvinylcaprolactame-based graft...

22. November 2016 Abstract The oral bioavailability of poorly soluble drugs can be improved by amorphization generated by loading into...

Abstract Associating protein with nanoparticles is an interesting strategy to improve their bioavailability and biological activity. Solid lipid nanoparticles (SLN)...

30. September 2016 ABSTRACT Oral dosage form is the physical form of a dose of a chemical compound used as...

14. September 2016 Abstract This work investigates whether the solubility of poorly soluble compounds can be improved by using mesoporous...

Traditionally, the melt granulation for pharmaceutical products was performed at low temperature (<90°C) with high-shear granulators using low-melting waxy binders,...