Fused Deposition Modeling (FDM), the new asset for the production of tailored medicines

8. November 2020

Over the last few years, conventional medicine has been increasingly moving towards precision medicine. Today, the production of oral pharmaceutical...

Co-administration of mini-tablets orlistat and xanthan gum

Anti-obesity effect with reduced adverse effect of the co-administration of mini-tablets containing orlistat and mini-tablets containing xanthan gum: In vitro and in vivo evaluation

28. October 2020

The purpose of this study was to develop an oral dosage form of orlistat for the treatment of obesity with...

Increasing water content in solvent during ASD drying

Water-Induced Phase Separation of Spray-Dried Amorphous Solid Dispersions

25. September 2020

Spray drying is widely used in the manufacturing of amorphous solid dispersion (ASD) systems due to its fast drying rate,...

Cannabidiol aqueous solubility enhancement: Comparison of three amorphous formulations strategies using different type of polymers

5. September 2020

Poor aqueous solubility of terpenophenolic compound Cannabidiol (CBD) is a major issue in the widespread use of this promising therapeutic...

Film forming systems for topical and transdermal drug delivery

31. August 2020

Methyl ester derivatives of alginic acid have been evaluated as potential multifunctional excipients for pharmaceutical direct compression. The use of...

Robustness Optimization of an Existing Tablet Coating Process Applying Retrospective Knowledge (rQbD) and Validation

13. August 2020

The objective of these studies is to verify and validate the improvement in the inter-tablet coating uniformity for an industrially...

Effect of the molecular mobility of water adsorbed by disintegrants on storage-induced hydrolytic degradation of acetylsalicylic acid incorporated into tablets under humid conditions

7. August 2020

The purpose of this study was to investigate the effect of molecular mobility of water adsorbed by disintegrants on the...

Compaction and tableting properties of composite particles of microcrystalline cellulose and crospovidone engineered for direct compression

21. July 2020

Excipients with improved functionality have continued to be developed by the particle engineering strategy of co-processing. The aim of this...

In-Depth Study into Polymeric Materials in Low-Density Gastroretentive Formulations

14. July 2020

The extensive use of oral dosage forms for the treatment of diseases may be linked to deficient pharmacokinetic properties. In...

Cushioning Pellets based on Microcrystalline Cellulose – Crospovidone Blends for MUPS Tableting

1. July 2020

Compaction of multiple-unit pellet system (MUPS) tablets has been extensively reported to be potentially challenging. Thus, there is a need...

Copovidone