Effect of Soluplus® on γ-cyclodextrin solubilization of irbesartan and candesartan and their nanoaggregates formation

5. January 2022

The poor aqueous solubility of irbesartan (IRB) and candesartan cilexetil (CAC) may hamper their bioavailability when orally or topically administered....

Transformation of nanoparticles into compacts: A study on PLGA and celecoxib nanoparticles

31. December 2021

Oral delivery of nanoparticles possesses many advantages for delivery of active pharmaceutical ingredients (APIs) to the gastrointestinal tract. However, the poor physical...

graphical abstract of Chitosan/cyclodextrin surface-adsorbed naringenin-loaded nanocapsules enhance bacterial quorum quenching and anti-biofilm activities

Chitosan/cyclodextrin surface-adsorbed naringenin-loaded nanocapsules enhance bacterial quorum quenching and anti-biofilm activities

27. December 2021

Pathogenic bacteria use quorum sensing (QS), a cell-to-cell communication process that uses small signalling molecules, to regulate several essential virulence...

graphical abstract of Food-grade olive oil Pickering emulsions stabilized by starch/β-cyclodextrin complex nanoparticles: Improved storage stability and regulatory effects on gut microbiota

Food-grade olive oil Pickering emulsions stabilized by starch/β-cyclodextrin complex nanoparticles: Improved storage stability and regulatory effects on gut microbiota

19. December 2021

The beneficial effects of olive oil consumption make it be one of the leading healthy edible oils worldwide. However, the water insolubility...

Development of fast-dissolving dosage forms of curcuminoids by electrospinning for potential tumor therapy application

3. December 2021

Curcuminoids (CUs) of antitumor and various other potential biological activities have extremely low water solubility therefore special formulation was elaborated....

graphical abstract of Cyclodextrin as Functional Carrier in Development of Mucoadhesive Tablets Containing Polygoni cuspidati Extract with Potential for Dental Applications

Cyclodextrin as Functional Carrier in Development of Mucoadhesive Tablets Containing Polygoni cuspidati Extract with Potential for Dental Applications

25. November 2021

Polygoni cuspidati root is a resveratrol-rich source with anti-inflammatory, angiogenic and neuroprotective effects. The raw material was standardized for the content...

Figure 7. Minimum Inhibitory Concentration (MIC) values of CEF and its different formulations against E. coli at t0 and after 1 and 2 weeks of storage at room temperature (RT) or at 4 °C.

Combined Use of Cyclodextrins and Amino Acids for the Development of Cefixime Oral Solutions for Pediatric Use

23. November 2021

Cefixime (CEF) is a cephalosporin included in the WHO Model List of Essential Medicines for Children. Liquid formulations are considered...

The rheological properties of the calcium hydroxide paste formulations: chlorhexidine-free calcium hydroxide paste (CH) and calcium hydroxide with 1% chlorhexidine (CHX) (10 × 103 mg/L): (a) frequency sweeps: determining G′ and G″ at a constant strain of 0.01%; (b) amplitude sweeps: determining G′ and G″ at a different shear strain; (c) time sweeps: evolution of the storage (G′) and loss (G″) moduli as a function of time at a frequency of 2.5 rad/s at 20 °C; (d) viscosity: shear-thinning evaluation by shear-rate dependent variations in viscosity.

How Adding Chlorhexidine or Metallic Nanoparticles Affects the Antimicrobial Performance of Calcium Hydroxide Paste as an Intracanal Medication: An In Vitro Study

12. November 2021

The aim of our study was to explore the potential value of metallic (Ag, Cu, and Zn) salts, polymer/metallic nanoparticles,...

Formulation of ternary genistein β-cyclodextrin inclusion complex: In vitro characterization and cytotoxicity assessment using breast cancer cell line

11. November 2021

Genistein (GT) is a poorly water-soluble flavonoid and reported for different biological activity. The present work was designed to prepare...

Fig. 3 - Structure of IBX in complex with the 70S ribosome, mRNA and tRNAs

A synthetic antibiotic class overcoming bacterial multidrug resistance

3. November 2021

The dearth of new medicines effective against antibiotic-resistant bacteria presents a growing global public health concern1. For more than five...

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