Hot-melt extrusion

Implantable drug delivery systems (IDDS) are an attractive alternative to conventional drug administration routes. Oral and injectable drug administration are...

Introduction Poly (lactic-co-glycolic acid) or PLGA, a highly hydrophobic copolymer comprised of lactic acid and glycolic acid, has been approved...

The current study aimed at optimizing a previously developed non-clinical formulation for use in zolpidem deprescribing. The formulation under investigation...

Additive manufacturing (AM) is an emerging pharmaceutical manufacturing technique feasible for patient-centric personalised medicine with tailored pharmacotherapy. Fused filament fabrication...

With two specifically engineered grades of polyvinyl alcohol, Merck´s Parteck® MXP polymers are optimal for generating high performing, solubility enhanced...

The objective of the current study is the formulation development and manufacturing of solid self-emulsifying delivery systems (HME S-SEDDS) via...

In situ gelling systems (ISGS) can prolong retention time and bioavailability of ophthalmic solutions. The complexity and cost of ISGS avert...

Three-dimensional (3D) printing is a powerful technology that has wide-ranging applications, including many in the pharmaceutical industry. 3D printing offers...

Hot-melt extrusion is increasingly applied in the pharmaceutical area as a continuous processing technology, used to design custom products by...

Poor solubility of active pharmaceutical ingredients (APIs) is a critical challenge in drug development. There are many avenues to improving...