Hot-melt extrusion

Hot Melt Extrusion (HME) technology was developed to obtain blends containing lyophilized Scutellariae baicalensis root extract and chitosan in order to improve...

Four model polymers, representing (i) amorphous homopolymers (Kollidon K30, K30), (ii) amorphous heteropolymers (Kollidon VA64, KVA), (iii) semi-crystalline homopolymers (Parteck...

The current healthcare dynamic has shifted from one-size-fits-all to patient-centred care, with our increased understanding of pharmacokinetics and pharmacogenomics demanding...

Hydroxypropyl methylcellulose (HPMC) is an important polymeric excipient. Its versatility in terms of molecular weights and viscosity grades is the...

The objective of this study was to increase the solubility of Mefenamic Acid (MA), a BCS class II drug by...

Hot-melt extrusion (HME) has an esteemed place in the pharmaceutical industry with significant applications and advancements spreading over 30 years...

The pharmaceutical industry needs innovative, new and novel excipients solutions to support the developments in next generation therapeutics, new manufacturing concepts (eg....

Hot-melt extrusion (HME) is used for the production of solid protein formulations mainly for two reasons: increased protein stability in...

Formulation of poorly water-soluble drugs is a significant challenge in the development of oral solid dosage forms. The objective was...

See the 4th Seminar on Amorphous Solid Dispersion. As technology provider in the field of ASD, Shin-Etsu together with the...