Hot-melt extrusion

The aim of this work was to compare mesoporous carriers based on silica and magnesium aluminosilicate in the amorphous solid...

The aim of this study was to couple fused deposition modelling 3D printing with melt extrusion technology to produce core–shell-structured...

The purpose of this study was to optimize the melt granulation process of fenofibrate using twin-screw granulator. Initial screening was...

Implantable drug delivery systems (IDDSs) offer good patient compliance and allow the controlled delivery of drugs over prolonged times. However,...

The aim of this study was to evaluate the benefits of a ternary amorphous solid dispersion (ASD) that was designed...

An industrially feasible approach to overcome the solubility and bioavailability limitations of poorly soluble active pharmaceutical ingredients is the development...

Enhancing the solubility of active drug ingredients is a major challenge faced by scientists and researchers. Different approaches have been...

Over the last few years, conventional medicine has been increasingly moving towards precision medicine. Today, the production of oral pharmaceutical...

The development of sustained-release formulations for drugs administered via the vaginal route has the potential to increase treatment efficiency and...

Hot-melt extrusion (HME) is the most preferred and effective method for manufacturing amorphous solid dispersions at production scale, but it...