Hot-melt extrusion

Abstract This study investigated the influence of solvent casting and hot-melt extrusion manufacturing methods on the physical, chemical, and functional...

This poster was presented at the ECP 2025 in Porto Introduction Hot melt extrusion (HME) is generally applied for the...

Abstract In recent years, there has been much interest in the development of personalized and on-demand tablets by FDM 3D-printing...

This poster was presented at the ECP 2025 in Porto Introduction Fig. 1. 20% drug-loaded particle microscopy before (A) and...

Abstract Background/Objectives: The oral delivery of large-molecule drugs remains challenging due to poor solubility, perdemeability, and stability in the gastrointestinal...

In the pharmaceutical industry, ensuring the bioavailability of active ingredients is crucial for the effectiveness of orally administered treatments. Bioavailability...

Itraconazole (ITZ), a BCS Class II drug exhibiting low solubility (1-4 ng/ mL in water) requires formulation enhancement to achieve...

In recent years, there has been much interest in three-dimensional (3D) printing for the development of personalized and on-demand medications...

Abstract Interest in hot-melt extrusion (HME) and fused deposition material (FDM) printing has increased in recent years, for the production...

Abstract Poor water solubility remains a significant challenge in the pharmaceutical industry that limits the therapeutic efficacy and bioavailability of...