HPMCAS - Hydroxypropyl methylcellulose acetate succinate

Understanding and controlling the drug solubilization in digestive environment is of great importance in the design of lipid based solid...

Amorphous solid dispersions feature prominently in the approach to mitigate low bioavailability of poorly water-soluble small molecules, particularly in the...

Amorphous solid dispersions have gained tremendous attention as a commercially viable solubility enhancement technique for poorly water-soluble drugs. However, poor...

The formulation development of amorphous solid dispersions (ASDs) towards a patient-friendly oral solid dosage form is proving to be still...

Inhibiting surface crystallization is an interesting strategy to enhance the physical stability of amorphous solid dispersions (ASDs), still preserving high...

Currently, there is a growing need to prepare small batches of enteric capsules for individual therapy or clinical evaluation since...

Atomic layer coating (ALC) is emerging as a particle engineering strategy to inhibit surface crystallization of amorphous solid dispersions (ASDs)....

Abstract Amorphous solid dispersions (ASDs) are among the most popular and widely studied solubility enhancement techniques. Since their inception in...

Preventing crystallization is a primary concern when developing amorphous drug formulations. Recently, atomic layer coatings (ALCs) of aluminum oxide demonstrated...

Abstract Poorly water-soluble drugs pose a significant challenge to developability due to poor oral absorption leading to poor bioavailability. Several...