HPMCAS - Hydroxypropyl methylcellulose acetate succinate

Various approaches have been developed to enhance the solubility or dissolution rate for the delivery of poorly water-soluble molecules. In...

Three-dimensional printing (3DP) is a widely used technique to manufacture drug delivery systems due to its precision, efficiency, and tailored...

Solid dispersion (SD) technology has been proved to be one of the most successful techniques to enhance aqueous solubility of...

Amorphous solid dispersion (ASD) is one of the most effective approaches for delivering poorly soluble drugs. In ASDs, polymeric materials...

Low oral absorption and extensive first pass metabolism of progesterone is reported for many oral formulations which warrants investigation into...

Galeterone, a novel prostate cancer candidate treatment, was discontinued after a Phase III clinical trial due to lack of efficacy....

Amorphous solid dispersions (ASDs) are commonly used to increase the dissolution rate of poorly soluble active pharmaceutical ingredients (APIs). Unfortunately,...

Understanding and controlling the drug solubilization in digestive environment is of great importance in the design of lipid based solid...

Amorphous solid dispersions feature prominently in the approach to mitigate low bioavailability of poorly water-soluble small molecules, particularly in the...

Amorphous solid dispersions have gained tremendous attention as a commercially viable solubility enhancement technique for poorly water-soluble drugs. However, poor...