HPMCAS - Hydroxypropyl methylcellulose acetate succinate

The antitumor drug candidate X-05 is being developed as an innovative anti-lung cancer drug candidate due to its excellent antitumour...

In this study, an amorphous solid dispersion containing the poorly water-soluble drug, bisacodyl, was prepared by hot-melt extrusion to enhance...

Abstract Amorphous solid dispersions (ASDs) enable formulations to improve the solubility of poorly soluble active pharmaceutical ingredients (APIs). The amorphous...

Various approaches have been developed to enhance the solubility or dissolution rate for the delivery of poorly water-soluble molecules. In...

Three-dimensional printing (3DP) is a widely used technique to manufacture drug delivery systems due to its precision, efficiency, and tailored...

Solid dispersion (SD) technology has been proved to be one of the most successful techniques to enhance aqueous solubility of...

Amorphous solid dispersion (ASD) is one of the most effective approaches for delivering poorly soluble drugs. In ASDs, polymeric materials...

Low oral absorption and extensive first pass metabolism of progesterone is reported for many oral formulations which warrants investigation into...

Galeterone, a novel prostate cancer candidate treatment, was discontinued after a Phase III clinical trial due to lack of efficacy....

Amorphous solid dispersions (ASDs) are commonly used to increase the dissolution rate of poorly soluble active pharmaceutical ingredients (APIs). Unfortunately,...