HPMCAS - Hydroxypropyl methylcellulose acetate succinate

Presently, a large number of drug molecules in development are BCS class II or IV compounds with poor aqueous solubility....

Amorphous solid dispersions (ASDs) are regarded as one of the most promising techniques for poorly-soluble active pharmaceutical ingredients (API). However,...

The bioavailability of insoluble crystalline active pharmaceutical ingredients (APIs) can be enhanced by formulation as amorphous solid dispersions (ASDs). One...

The aim of the current study was to investigate the dual effect of an amorphous solid dispersion generated by hot...

This review aims to provide the state of the art on polymeric and lipid nanoparticles, used or suggested to approach...

The absorption of oral drugs is frequently plagued by significant variability with potentially serious therapeutic consequences. The source of variability...

Amorphous solid dispersions (ASDs), which consist of a drug dispersed in a polymeric matrix, are increasingly being applied to improve...

Polymers are essential components of many drug delivery systems and biomedical products. Despite the utility of many currently available polymers,...

Poorly water-soluble drugs frequently solubilize into bile colloids and this natural mechanism is key for efficient bioavailability. We tested the...

In this study Fusion Deposition Modelling (FDM) was employed to design and fabricate a bilayer tablet consisting of isoniazid (INZ)...