Downstream Processing of Amorphous and Co-Amorphous Olanzapine Powder Blends

29. July 2022

The work evaluates the stability of amorphous and co-amorphous olanzapine (OLZ) in tablets manufactured by direct compression. The flowability and...

Development and Use of a Residence Time Distribution (RTD) Model Control Strategy for a Continuous Manufacturing Drug Product Pharmaceutical Process

28. July 2022

Residence-time-distribution (RTD)-based models are key to understanding the mixing dynamics of continuous manufacturing systems. Such models can allow for material...

Development of a long-acting tablet with ticagrelor high-loaded nanostructured lipid carriers

15. July 2022

Ticagrelor (TCG), an antiplatelet agent, has low solubility and permeability; thus, there are many trials to apply the pharmaceutical technology...

Biochar as a processing additive in poly (butylene adipate-co-terephthalate) (PBAT)

13. July 2022

Poly (butylene adipate-co-terephthalate) (PBAT) is a promising alternative to non-biodegradable plastics in agricultural applications. However, it is usually blended with...

Data-driven approach to mitigate quality impact of hygroscopic pharmaceutical raw materials throughout the supply chain

28. June 2022

The challenges of working with hygroscopic pharmaceutical raw materials can have a significant impact on the industry’s ability to make...

Development of Nafamostat Mesylate Immediate-Release Tablet by Drug Repositioning Using Quality-by-Design Approach

15. June 2022

We aimed to develop nafamostat mesylate immediate-release tablets for the treatment of COVID-19 through drug repositioning studies of nafamostat mesylate...

Gastroretentive Sustained-Release Tablets Combined with a Solid Self-Micro-Emulsifying Drug Delivery System Adsorbed onto Fujicalin®

11. June 2022

Gastroretentive drug delivery systems (GRDDS) get retained in the stomach for a long time, thus facilitating the absorption of drugs...

Solubility Enhancement of Ibuprofen by Adsorption onto Spherical Porous Calcium Silicate

2. June 2022

The solubility of a drug is higher when it is in an amorphous form than when it is in a...

Impact of unloading kinematics on the occurrence of capping during the production of pharmaceutical tablets

18. May 2022

Capping is a common defect that can occur during the manufacturing of pharmaceutical tablets. Several studies showed that decreasing the...

overview inorganica and organic carriers CaCo3

Hard, Soft, and Hard-and-Soft Drug Delivery Carriers Based on CaCO3 and Alginate Biomaterials: Synthesis, Properties, Pharmaceutical Applications

11. May 2022

Because free therapeutic drug molecules often have adverse effects on normal tissues, deliver scanty drug concentrations and exhibit a potentially...

Inorganic Chemicals