Liquids

Abstract Co-administration of oral drug products with dosing vehicles is common practice in pediatric drug administration. The present work focused...

See the presentation of Lukas Ries from BASF at the 6th APV Continuous Manufacturing Conference 2025: Conventional wet granulation requires...

Abstract Posaconazole (PCZ) is a broad spectrum anti-fungal drug approved by FDA and currently used off-label for the treatment of...

Abstract The opioid-like characteristics of mitragynine with biased μ-opioid receptor activation are attractive for pain and addiction therapy due to...

Abstract N-nitrosamine compounds have long been known for their carcinogenic properties, but they came into the focus of the pharmaceutical...

Abstract Protein-based drugs are prone to both physical and chemical instability in aqueous solutions. Surfactants, such as polysorbates (PS), are...

Introduction Gamma‑hydroxybutyrate (GHB) is an endogenous neurotransmitter also used pharmaceutically—usually as sodium oxybate—for treating narcolepsy and related disorders. It exerts...

Abstract Amphotericin B (AmB) is used to treat Allergic Bronchopulmonary Aspergillosis (ABPA) caused by Aspergillus fumigatus. AmB is available in oral...

Abstract An industrial-scale pharmaceutical powder blending process was studied via discrete element method (DEM) simulations. A DEM model of two...

Abstract The present study focuses on the development and optimization of a solid self-microemulsifying drug delivery system (SSMEDDS) of Nateglinide,...