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The sticking of active pharmaceutical ingredient (API) to the surfaces of compaction tooling, frequently referred to as punch sticking, causes...
Abstract In this study, an integrated flowsheet model of the continuous feeder-mixer system was calibrated, simulated and compared against experimental...
Abstract Continuous manufacturing is becoming the new technological standard in the pharmaceutical industry. In this work, a twin-screw processor was...
This study describes the first implementation of Raman spectrometer in a stream sampler for the in-line monitoring of low drug...
See the sixth issue of Fuji Chemical Industries Technical Newsletter: Directly compressible excipient system for fast-Disintegrating oral tablets*, F-MELT® formulations...
The purpose of this study is to derive an optimal drug release formulation with human clinical bioequivalence in developing a...
The aim of this feasibility study was to investigate the possibility of producing industrial-scale relevant, robust, high drug-loaded (90.9%, w/w) 100...
Modeling of structural and mechanical tablet properties consisting of multiple components, based on a minimum of experimental data is of...
The current paper shows how excipient properties impact the process parameters and the final tablet properties in a fully integrated continuous direct...
Twin-screw continuous mixing was used to prepare aerosol powders containing 1% budesonide, 0.3% magnesium stearate, and 98.7% α-lactose monohydrate. The effect of...
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