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Abstract Pharmaceutical tablet formulation and process development, traditionally a complex and multi-dimensional decision-making process, necessitates extensive experimentation and resources, often...
Purpose There are scarce reports on in vitro-in vivo correlation (IVIVC) model development of immediate-release (IR) formulations, and few investigations of the...
See another MEDELPHARM bulletin: Amorphous solid dispersions (ASDs) have been widely used to improve the bioavailability of poorly water-soluble drugs...
The mixing of ductile lubricant particles is known to have several negative effects on tablet properties, such as decreased hardness...
ABSTRACT: Piroxicam is an oxicam class of NSAID which is a drug of choice in the treatment of severe pains...
Background/Objectives: Mini-tablets are a novel pediatric dosage form designed to mask drug taste and facilitate easier administration. This study aimed...
The pharmaceutical industry has been shifting towards continuous manufacturing, specifically for tablet production. Compared to batch processing, continuous tableting exhibits...
Abstract Powder flow characteristics are crucial for efficient processing and manufacturing in the pharmaceutical industry. The occurrence of tribo-charging, a...
Hydroxypropyl methylcellulose (HPMC) is a commonly used excipient to enable controlled release (CR) performance from a hydrophilic matrix tablet. Quality-by-Design...
Abstract This study aims to investigate the effects of the relative humidity and formulation ratio on the hygroscopicity, tableting performance,...
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