Mannitol

This study tested 15 direct compaction grades to identify the contribution of different grades of mannitol to the storage stability...

Granule structure has a key influence on tablet critical quality attributes. The ability to control this structure through excipient choice...

Performance of orally disintegrating tablets (ODTs) with GRANFILLER-D was investigated by the real-time X-ray observation of water penetration into ODTs....

This paper demonstrated that a novel enteric osmotic pump capsule (EOPC) could effectively deliver metformin hydrochloride (MH) into the small...

More than 10 years after the Paediatric Regulation came into place there is still a strong need for pure paediatric medicines...

Highlights • Twin-screw granulation was less sensitive for liquid amount used. • API compaction properties had only minor effect on...

Orally disintegrating tablets (ODTs) manufactured by freeze-drying, also called oral lyophilizates, are a patient-centred dosage form. They possess ultra-fast disintegration...

Effective vaccine delivery and coverage to rural and resource-poor countries is hindered by the dependence on cold chain storage. As...

The objective of these studies is to verify and validate the improvement in the inter-tablet coating uniformity for an industrially...

The purpose of this study was to investigate the effect of molecular mobility of water adsorbed by disintegrants on the...