Mannitol

The improvement of drug solubility is a challenging task in the pharmaceutical industry; moreover, drug stability is also important. This...

A model anaerobic bacterium strain from the gut microbiome (Clostridium butyricum) producing anti-inflammatory molecules was incorporated into polymer-free fibers of...

Orally Disintegrating Tablets (ODTs) are getting increasingly interesting delivery systems in the pharmaceutical and nutraceutical fields. They are an innovative way...

The internal blending of magnesium stearate is often associated with decreasing tensile strengths and longer disintegration and dissolution times. Therefore,...

Elucidating the impact of excipient variability on oral product performance in a biopharmaceutical perspective would be beneficial and allow excipient...

Typically, smooth lactose particles are used as carrier in dry powder formulations for inhalation. Two classical approaches to improve their...

A 7-month-old female patient with B-cell acute lymphoblastic leukemia (ALL) developed recurring anterior fontanelle bulging after completing both of her...

Compression of cohesive, poorly compactable, and high-dose metformin hydrochloride into the orally disintegrating tablet (ODT) is challenging. The objective of...

Due to the complexity and fragility of biological drug products, several challenges exist in their formulation development. Excipients are added...

Spray-freeze-drying (SFD) is a process in which a solution is dispersed into a freezing medium and dried by sublimation, resulting...