5 solutions to common formulation challenges

1. Trouble finding a soluble DC filler/binder with pleasant taste and mouthfeel for non-GMO, lactose free formulations?

TRY EMDEX® – REQUEST A SAMPLE

EMDEX® is a directly compressible, water-soluble tablet binder and filler. Its unique composition of 95% glucose monohydrate and different oligosaccharides derived from starch is monographed under “dextrates” in the NF. With use levels ranging from 1% to 99%, EMDEX® is designed for a variety of tablet applications.
Download the brochure here: emdex-gb-1609

2. Looking for an all-in-one, high functionality excipient composite ideal for continuous manufacturing?

Try PROSOLV® EASYtab SP – REQUEST A SAMPLE

In a continuous process, mono-functional excipients must be added through individual feeders, possibly resulting in multiple sources of variability. Alternatively, a single high-functionality co- processed excipient can accomplish the same task using only one feeder, thus enhancing finished product performance while keeping variability to a minimum. This paper will cover how using one high-functionality excipient can provide significant benefits over using multiple traditional mono-functional excipients.
Download Benefits of Using High- Functionality Excipients in a Continuous Manufacturing Process

3. Compromising your tablet integrity or API dissolution with commonly used lubricants?

TRY PRUV® – REQUEST A SAMPLE

PRUV®, Sodium Stearyl Fumarate, is a tablet lubricant specifically designed for formulations in which other lubricants lead to formulation and/or manufacturing challenges. As opposed to magnesium stearate, it offers advantages including: high degree of API compatibility, robustness to over-lubrication, no adverse effect on bioavailability, and improved appearance of effervescent solutions.
Download the brochure here: Pruv Sodium Stearyl Fumarate

4. Complications with poor flow, loss of compactibility, or sensitivity to lubricants?

TRY PROSOLV® SMCC – REQUEST A SAMPLE

Over 20 years ago, JRS PHARMA developed a new and innovative excipient, PROSOLV® SMCC (silicified microcrystalline cellulose), to alleviate some of the known deficiencies of conventional binders including: low bulk density, poor flow, loss of compatibility, stickiness issues, and sensitivity to lubricants. PROSOLV® SMCC not only addresses these challenges, but also offers enhanced performance.
Download the brochure here: PROSOLV® SMCC

5. Difficulties with your liquid binder giving you low granule strength?

TRY VIVAPHARM® PVP – REQUEST A SAMPLE

VIVAPHARM® PVP K30 is the classic wet binder with optimal balance between adhesive strength and ease of handling. It has excellent solubility in water and a range of organic solvents, and is supplied as a free-flowing powder with spherical particle morphology. This ensures rapid dispersibility and ultimate flexibility in the solvent of choice.
Download the brochure here: VIVAPHARM-PVP