Amorphous Solid Dispersions – Ask a Specialist!
More and more poorly water-soluble or even water-insoluble drug candidates show up in pharmaceutical development. Achieving a good bioavailability and efficacy requires technical platforms and processes. Solid dispersions and amorphous solid dispersions are well established and proven approaches to overcome the API solubility issue.
We did a well-attended live webcast on this topic with the expert Dr. Norbert Pöllinger from Glatt Pharmaceutical Services. He presented Glatt’s tools and technology platforms and answered a lot of questions related to amorphous solid dispersion.
To share this knowledge with the excipients community we made some composites of the video. Also you can view the full recording for free (see the link a bit down on this page).
If you have additional questions on Amorphous Solid Dispersions? We are doing a “Ask a specialist” campaign for this topic. So send us your question related to Amorphous Solid Dispersions and Dr. Pöllinger from Glatt Pharmaceutical Services will try to answer and help you. We will also publish all the answers on pharmaexcipients.com.
Creation and role of amorphous solid dispersion with subtitles:
To watch full Glatt webcast, submit your name and mail. The link will appear directly.
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Questions asked by participants:
Question: How do we get denser granules?
Question: How do you separate the powder from air in the fluid bed?
Question: What are the options to avoid stability issues besides protecting from moisture?