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Polymeric nanofiber systems for the encapsulation and delivery of biological entities in food, pharmaceutical, and biomedical fields
Polymeric nanofiber systems for the encapsulation and delivery of biological entities in food, pharmaceutical, and biomedical fields
Abstract
Biological entities encompass all living or once-living components of the natural world, including molecules, cells, and organisms. Recent advancements have demonstrated the potential of incorporating small molecules, living cells, and microorganisms into nanofibers for biomedical applications.
Highlights
- Biological entities are integrated into electrospun nanofibers for biomedical use.
- Electrospinning effectively incorporates biological components into viable nanofibers.
- These nanofibers support the sustained release of small molecules and cells.
- This technique shows promise in regenerative medicine, food, and biocatalysis.
This interdisciplinary method merges nanofibers’ distinctive characteristics with living entities’ biological functions to tackle issues in regenerative medicine. Methods like electrospinning have successfully incorporated biological components into nanofibrous structures while preserving their viability and activity.
These hybrid constructs create a conducive microenvironment that encourages cell growth, proliferation, and differentiation, thus aiding tissue regeneration. Furthermore, this cutting-edge technique is helpful in the food sector and in biocatalytic contexts. This review examines the incorporation of biological entities into nanofibers and investigates their possible applications.
Continue reading here
Rajkumar Patel, Pratheep Kumar Annamalai, Ramanujam Brahmadesam Thoopul Srinivasa Raghava, Madhumita Patel, Polymeric nanofiber systems for the encapsulation and delivery of biological entities in food, Pharmaceutical, and biomedical fields, Reactive and Functional Polymers, 2025, 106552, ISSN 1381-5148, https://doi.org/10.1016/j.reactfunctpolym.2025.106552.
Read more on electrospinning here:
- Novel Strategies for the Formulation of Poorly Water-Soluble Drug Substances by Different Physical Modification Strategies with a Focus on Peroral Applications
- Poorly water-soluble APIs in fixed-dose combinations: development, challenges, and opportunities in manufacturing techniques
- Formulation and Characterization of Novel Oral pH-Sensitive Electrospun Nanofibers for Boosting Dissolution and Penetration of Model Class IV Drug
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