Omyanutra® 300 DC – Direct compressible, porous excipient for nutraceuticals

Producing nutraceuticals in solid dosage form is complex and faces many challenges. In production, manufacturers choose either wet or dry granulation, or, which is becoming more popular, direct compression. Direct compression (DC) results in the shortest, most efficient and least complex way to produce tablets. Additionally, the DC tableting method is most suitable for moisture- or heat- sensitive ingredients, like herbal extracts or essential oils.

SEM image Omyanutra® 300 DC
SEM image Omyanutra® 300 DC

Despite its many benefits, direct compression, however, requires a critical selection of the excipient, contrary to the granulation methods since the raw material isn’t further processed before tableting. Free-flowing and highly compressible excipients like Omyanutra® 300 DC are required for a successful directly compressed tablet.

Omyanutra® 300 DC is the direct compressible version of the Omyanutra® 300 excipient. The free-flowing granules of the DC-variant allow for easy manufacturing, resulting in less tablet weight variability and much more compactable tablets. Due to its high compactability, tablets containing Omyanutra® 300 DC feature increased mechanical stability which leads to less tablet friability.

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See the teaser about Omyanutra® 300 DC here:


Omyanutra® 300 DC offers superior compactability than benchmarks such as lactose and microcrystalline cellulose (MCC). In addition, the mineral provides fast disintegration thanks to the particles’ porous structure. This porosity also enables easy carrying and release of active ingredients.

Omyanutra® 300 DC is based on functionalized calcium carbonate (FCC). FCC is natural calcium carbonate that became a new mineral composition and structure, through a recrystallization process.

Benefits:

  • Direct compressible excipient
  • Easier manufacturability
  • Hard tablets at low compression forces
  • Superior compactability

Features:

  • Free-flowing, direct compressible granules
  • Porosity allows for carrying and release of actives
  • Made from high-purity, natural mineral
  • Non-nano engineered, non-GMO material

Click images to enlarge

Omyanutra 300 DC - compactibility

Omyanutra 300 DC - compactibility

Omyanutra 300 DC - disintegration time_tablet hardness

Omyanutra 300 DC product brochure first pageDownload the full brochure as a PDF here


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