Sustained-Release Solid Dispersions of Fenofibrate for Simultaneous Enhancement of the Extent and Duration of Drug Exposure
Abstract
Background/Objectives: A sustained-release formulation of fenofibrate while enhancing drug dissolution with minimal food effect is critical for maximizing the therapeutic benefits of fenofibrate. Therefore, this study aimed to develop an effective solid dispersion formulation of fenofibrate for simultaneous enhancement in the extent and…
CPhI Worldwide proposes new FDA quality metrics system
26. September 2016
CPhI Worldwide, organized by UBM EMEA, has announced the findings of part i of the 2016 CPhI Annual Report on potential new approaches to improve quality and manufacturing process in pharmaceutical…
Moving toward a paradigm shift in the regulatory requirements for pediatric medicines
25. September 2016 Abstract Over the past two decades, there has been growing concern over the lack of proper medication for children. This review attempts to evaluate…
Physicochemical properties of direct compression tablets with spray dried and ball milled solid…
25. September 2016 Abstract The aim of this research was to develop immediate release tablets comprising solid dispersion (IRSDTs) of tadalafil (Td) in a vinylpyrrolidone…
An Overview on Regulatory Mechanism for Pharmaceutical Excipients in Regulated Market
22. September 2016 Abstract: Background: In this era of evolution, quality and safety of pharmaceutical dosage forms have been given a prime importance. In this context,…
Characterization and quantification of pH sensitive polymers used in drug targeting by inverse-phase…
22. September 2016
Characterization and quantification of pH sensitive polymers used in drug targeting by inverse-phasegas chromatography and dynamicvapour sorption techniques
Surface energies and dynamic vapour sorption (DVS)…
Dow and Colorcon broaden the scope of their Controlled Release Alliance
22. September 2016 Colorcon and Dow Chemical have agreed to extend and broaden their Controlled Release Alliance. The Alliance currently provides controlled release…
CELLULOSIC ON TRANSDERMAL DRUG DELIVERY SYSTEM: A REVIEW
21. September 2016 ABSTRACT Transdermal patch is a medicated adhesive patch that is placed on the skin to deliver the drug through the skin in order to achieve systemic…
Adaptation of pharmaceutical excipients to FDM 3D printing for the fabrication of patient-tailored…
21. September 2016 Abstract This work aims to employ fused deposition modelling 3D printing to fabricate immediate release pharmaceutical tablets with various model…
The Properties of HPMC:PEO Extended Release Hydrophilic Matrices and their Response to Ionic…
21. September 2016 Purpose Investigate the extended release behaviour of compacts containing mixtures of hydrophilic HPMC and PEO in hydrating media of differing ionic…
Fast dissolution of poorly water soluble drugs from fluidized bed coated nanocomposites: Impact of…
20. September 2016 Abstract Formation of core-shell nanocomposites of Fenofibrate and Itraconazole, model poorly water soluble drugs, via fluidized bed (FB) coating of…
Polymorphism of D-mannitol: Crystal structure and the crystal growth mechanism
20. September 2016 Abstract The polymorphism of D-Mannitol (mannitol) is reviewed in this paper. It was found that the structure of the stable form is consistent in most…
Evaluation of taste masking effect of diclofenac using sweeteners and cyclodextrin by a…
20. September 2016 Abstract In this work a potentiometric electronic tongue based on classical ion-selective electrodes (6 types) and solid contact electrodes (2 types)…
CELANESE PRESENTS INNOVATIONS IN EVA POLYMERS AT TARGETING OCULAR DISORDERS CONFERENCE
19. September 2016 Improving drug delivery to the eye with Celanese EVA polymers DALLAS and BOSTON, Mass. (September 15, 2016) – Celanese Corporation (NYSE: CE), a…
Hydrodynamic size characterization of a self-emulsifying lipid pharmaceutical excipient by Taylor…
18. September 2016 Abstract In this work, the sizing of microemulsion droplets of a lipid-based pharmaceutical excipient (Labrasol® ALF) is performed by Taylor dispersion…
Rational Design of Multifunctional Dendritic Mesoporous Silica Nanoparticles to Load Curcumin and…
18. September 2016 Breast cancer is the primary cause of cancer-related death in women worldwide and its management remains a challenge in everyday oncology practice. Thus,…
Colonic Drug Targeting Approaches for Treatment of Inflammatory Bowel Disease
18. September 2016
Inflammatory bowel disease (IBD) is an idiopathic, relapsing disease involving chronic inflammation of the digestive tract, either in part or entire. IBD primarily includes Crohn’s disease (CD) and…
Formulation and Development of Colon Specific Multiparticulate System of Capecitabine
18. September 2016 Aim: In the present study, the main objective was to develop a multiparticulate system containing chitosan microspheres for colon-specific drug delivery…
Development and Characterization of a Microemulsion System Containing Amphotericin B with Potential…
18. September 2016 Abstract: Background: Amphotericin B eye drops are widely used in the treatment of ocular infections. However, amphotericin’s toxicity leads to low…
Design of experiment approach in development of febuxostat nanocrystal: Application of Soluplus® as…
14. September 2016 Abstract The objective of present study was to explore the application of Soluplus® as a stabilizer for the preparation of febuxostat (FEB)…
Mechanism by Which Magnesium Oxide Suppresses Tablet Hardness Reduction during Storage
14. September 2016
Abstract
This study investigated how the inclusion of magnesium oxide (MgO) maintained tablet hardness during storage in an unpackaged state. Tablets were prepared with a range of MgO levels and stored…
Supersaturation of poorly soluble drugs induced by mesoporous magnesium carbonate
14. September 2016
Abstract
This work investigates whether the solubility of poorly soluble compounds can be improved by using mesoporous magnesium carbonate (MMC) as the drug delivery system. A solvent evaporation method…
Deposition of Ibuprofen crystals on Hydroxypropyl Cellulose/Polyacrylamide Gel: Experimental and…
14. September 2016 Abstract This research study aimed to develop a new strategy for using a polymer blend in solid dispersion (SD) for dissolution enhancement of poorly…
Current Practices in Solid Dosage Form Processing Seminar
14. September 2016
October 18 - 20, 2016
Doubletree Hotel - 180 Route 17 South - Mahwah, New Jersey
Program & Registration Form
PTS 2016 BROCHURE.pdf
Adobe Acrobat Document…
«galenIQ™ – The functional filler-binder that enables medicine to taste better» –…
13. September 2016
Basel - Friday, November 25, 2016
Michael Black, Beneo
- Why galenIQ™ is the solution for you
- Sensory properties of galenIQ™
- What is galenIQ™ and how can you use it?…
The Effect of Commonly Used Excipients on the Epithelial Integrity of Human Cervicovaginal Tissue
13. September 2016 Pharmaceutical excipients are widely used in vaginal drug products. The epithelial integrity of the cervicovaginal tissue is important for HIV-1…
Nasal Absorption of Macromolecules from Powder Formulations and Effects of Sodium Carboxymethyl…
13. September 2016 Abstract The nasal absorption of macromolecules from powder formulations and the effect of sodium carboxymethyl cellulose (CMC-Na) as a pharmaceutical…
Controlled, pulsatile release of thermostabilized inactivated polio vaccine from PLGA-based…
13. September 2016 Abstract Many vaccines, such as the inactivated polio vaccine (IPV), must be administered in several doses for full efficacy. Because patient access is…
Deposition of Ibuprofen crystals on Hydroxypropyl Cellulose/Polyacrylamide Gel: Experimental and…
13. September 2016 ABSTRACT The crystallization of nonsteroidal anti-inflammatory drug ibuprofen (IBP) on a hydroxypropyl cellulose (HPC) and polyacrylamide (PAAm) gel…
Workshop on Methods for Accelerating Scalable Bioprocess Development
13. September 2016 QbD oriented methodology for efficient and robust development of biopharmaceutical processes November 10th/11th 2016 Hotel Savoyen…
AirLiquide Benelux receives EXCiPACT Certificate
12. September 2016
AirLiquide Benelux receives EXCiPACT Certificate
EXCiPACT asbl is pleased to announce that Air Liquide Benelux Industries' Marchienne-au-Pont Charleroi site has recently been awarded an EXCiPACT Certificate…
Simplified approach to drug development with Upsalite – Mesoporous magnesium carbonate
11. September 2016 For the first time, researchers have revealed the nanostructure of the mesoporous magnesium carbonate Upsalite and pore size control was achieved without…
Excipient Learning Lab – Webcast- September 14-15, 2016
11. September 2016
IPEC Webinars On Demand here
IPEC Education and Training here
Excipient Learning Lab – Self paced on-line course, available anytime with 14 day access
11. September 2016 Excipient Learning Lab - Self paced on-line course, available anytime with 14 day access Date: N/A (Self paced on-line course,…
Excipient Learning Lab – Workshop – October 18-20, 2016
11. September 2016
Excipient Learning Lab - Workshop - October 18-20, 2016
Arlington, VA - 8:30-4:30 EDT
Excipient GMP Compliance Workshop for Auditors & Auditees