Hot melt extrusion with PVA: A new opportunity for challenging APIs

In this webcast, you will learn:

• about amorphous solid dispersions and their preparation by hot melt extrusion
• how to identify the right polymer at early development stages
• how to improve the performance of your formulation by using polyvinyl alcohol

Detailed description:

Hot melt extrusion is considered to be one of the most effective technology for the creation of solid dispersion. Its rapid advancement in the development of new pharmaceutical products highlights its importance.

In this webcast you will learn about the potential of hot melt extrusion technology to overcome challenges in solubility and bioavailability of drug substances by using polyvinyl alcohol (PVA) as a matrix polymer.

We will provide an overview about different types of solid dispersions and their evolution in the pharmaceutical field. A brief introduction in hot melt extrusion processing will be given as well as an overview of actual formulation trends.

You will gain insights in novel screening tools for hot melt extrusion which can represent a decisive strategic advantage at early development stages. A detailed background of PVA will be provided including its physical properties as well as its regulatory status. Due to its amphiphilic structure it has the potential to improve the supersaturation of low soluble APIs and to prevent precipitation after release.

Another aspect involves the versatile down-stream options to create your final dosage form as well as innovative applications.

Register here :“Hot melt extrusion with PVA “