Daily multi-segment capsule for time-tunable drug release toward enhanced polypharmacy adherence

2. February 2025

Progress and potential We have developed a tunable, multi-segment daily capsule to advance polypharmacy, enhance adherence to medication regimens, and...

Design, evaluation, and in vitro–in vivo correlation of self-nanoemulsifying drug delivery systems to improve the oral absorption of exenatide

1. February 2025

Abstract The ability to predict the absorption of exenatide (Ex), a GLP-1 analogue, after oral dosing to rats in self-nanoemulsifying...

Oral colon-targeted responsive chitosan/pectin-based nanoparticles propels the application of tofacitinib in colitis therapy

1. February 2025

Abstract Tofacitinib (Tof), a commercially available pan-Janus kinases inhibitor, is approved for the treatment of moderate to severe ulcerative colitis....

Pediatric Formulation Optimization Using a Rational Design: Exploring Amorphous Solid Dispersion Technology with Terbinafine Hydrochloride as a Case Study

31. January 2025

Abstract Developing orally administered pediatric formulations presents significant challenges due to the unique characteristics of pediatric patients. Terbinafine hydrochloride (TER),...

Applications of Sorbitan Esters – by KLK Kolb

30. January 2025

KLK Kolb excipients, marketed under the Hedjuvan brand, are all produced at the Hedingen facility in Switzerland. These versatile excipients...

Alginate coated mesoporous silica nanoparticles as oral delivery carrier of curcumin and quercetin to colon cancer: preparation, optimization, characterization, and anticancer activity

26. January 2025

Abstract The synergistic bioactive effect of polyphenols can enhance the development of functional foods to prevent chronic diseases such as...

Oral Excipients