High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticl

High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: physicochemical, structural and pharmacokinetic performances

23. January 2023

Preclinical development of deuterated pyrazoloquinolinone ligands, promising drug candidates for various neuropsychiatric disorders, was hindered by unusually low solubility in...

Insights into the Multiscale Lubrication Mechanism of Edible Phase Change Materials

21. January 2023

Investigation of a lubrication behavior of phase change materials (PCM) can be challenging in applications involving relative motion, e.g., sport (ice...

Transform Your Brick-Dust API into an Effective oral Drug Candidate with Apinovex Polymers

19. January 2023

Lubrizol Apinovex™ polymers can be easily incorporated into your drug project via spray drying or other solvent-based processes. This novel...

A new oral self-emulsifying drug delivery system improves the antileishmania efficacy of fexinidazole in vivo

17. January 2023

The aim of this study was to develop, characterize and evaluate the in vivo oral efficacy of self-emulsifying drug delivery systems (SEDDS)...

Advances in Formulation and Manufacturing Strategies for the Delivery of Therapeutic Proteins and Peptides in Orally Disintegrating Dosage Forms

12. January 2023

Therapeutic proteins and peptides (TPPs) are increasingly favoured above small drug molecules due to their high specificity to the site...

Apinovex Polymers Enable Solubility With Ease

10. January 2023

Apinovex™ polymers can be easily incorporated into your drug project via spray drying or other solvent-based processes. This novel excipient...

Solubility Enhanced Formulation Approaches to Overcome Oral Delivery Obstacles of PROTACs

9. January 2023

PROteolysis TArgeting Chimaeras (PROTACs) offer new opportunities in modern medicine by targeting proteins that are undruggable to classic inhibitors. However,...

Advanced Strategies of Drug Delivery via Oral, Topical, and Parenteral Administration Routes: Where do Equine Medications Stand?

8. January 2023

While the global market for veterinary products has been expanding rapidly, there is still a lack of specialist knowledge of...

Incorporating a Lipophilic Disulfide-Bridged Linoleic Prodrug into a Self-Microemulsifying Drug Delivery System to Facilitate Oral Absorption of Paclitaxel

7. January 2023

The oral absorption of paclitaxel (PTX) is restricted by poor solubility in the gastrointestinal tract (GIT), low permeability, and high...

Processability and Oral Bioavailability Improvement of Itraconazole by Particle Engineering Technique

6. January 2023

The current study aimed to improve the processability and oral bioavailability of itraconazole (ITZ) via spherical agglomeration. ITZ-spherical agglomerates (ITZ-SA)...

Oral Excipients

High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: physicochemical, structural and pharmacokinetic performances

Insights into the Multiscale Lubrication Mechanism of Edible Phase Change Materials

Transform Your Brick-Dust API into an Effective oral Drug Candidate with Apinovex Polymers

A new oral self-emulsifying drug delivery system improves the antileishmania efficacy of fexinidazole in vivo

Advances in Formulation and Manufacturing Strategies for the Delivery of Therapeutic Proteins and Peptides in Orally Disintegrating Dosage Forms

Apinovex Polymers Enable Solubility With Ease

Solubility Enhanced Formulation Approaches to Overcome Oral Delivery Obstacles of PROTACs

Advanced Strategies of Drug Delivery via Oral, Topical, and Parenteral Administration Routes: Where do Equine Medications Stand?

Incorporating a Lipophilic Disulfide-Bridged Linoleic Prodrug into a Self-Microemulsifying Drug Delivery System to Facilitate Oral Absorption of Paclitaxel

Processability and Oral Bioavailability Improvement of Itraconazole by Particle Engineering Technique

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