A mucoadhesive patch loaded with freeze-dried liposomes for the local treatment of oral tumors

9. September 2022

Oral cancers affect millions of people globally, with increasing incidences among adults aged 35 and above. Poor drug uptake by...

LipMetE (Lipophilic Metabolism Efficiency) as a Simple Guide for Half-Life and Dosing Regimen Prediction of Oral Drugs

8. September 2022

The in vivo half-life is a key property of every drug molecule, as it determines dosing regimens, peak-to-trough ratios and...

Oral drug delivery strategies for development of poorly water soluble drugs in paediatric patient population

5. September 2022

Selecting the appropriate formulation and solubility-enabling technology for poorly water soluble drugs is an essential element in the development of...

The influence on the oral bioavailability of solubilized and suspended drug in a lipid nanoparticle formulation: In vitro and in vivo evaluation

2. September 2022

The present study investigated the oral bioavailability of celecoxib when incorporated into solid lipid nanoparticles either dissolved or suspended. In vitro drug...

StarLac – MEGGLE’s co-processed lactose grades for direct compression

1. September 2022

General Information Direct compression (DC) tablet manufacture is a popular choice because it provides the least complex, most cost effective...

Development of Inline Near-Infrared Spectroscopy Method for Real-Time Monitoring of Blend Uniformity of Direct Compression and Granulation-Based Products at Commercial Scales

1. September 2022

Blending is a critical intermediate unit operation for all solid oral formulations. For blend uniformity testing, API content in the...

Enhancement of the Bioavailability and Anti-Inflammatory Activity of Glycyrrhetinic Acid via Novel Soluplus®—A Glycyrrhetinic Acid Solid Dispersion

31. August 2022

Glycyrrhetinic acid (GA) is an anti-inflammatory drug with potential for development. However, the poor solubility of GA in water leads...

Oral Excipients