Effect of Carrier Type and Tween® 80 Concentration on the Silymarin Release from the Solid Dispersion

9. November 2020

The following poster was presented first at AAPS PharmSci 360 in October 2020. We had the chance to get a...

An investigation into applicability of different compression behaviour assessment approaches for multiparticulate units characterization

8. November 2020

Increasing expectations to understand material properties and process parameters impact on drug product performance resulted in increased efforts towards evaluation...

Historic evolution of the number of available formulations. (a) Combined DrugBank and Pillbox data track the number of different formulations of the same APIs available to patients over time, ranked by number of formulations available in 2019. (b) Average number of available formulations per API. (c) Correlations of the number of formulations available for the 300 most prescribed medications of 2019.

Historical Evolution and Provider Awareness of Inactive Ingredients in Oral Medications

2. November 2020

Purpose: A multitude of different versions of the same medication with different inactive ingredients are currently available. It has not...

graphical abstract of Bioavailability Improvement of Carbamazepine via Oral Administration of Modified-Release Amorphous Solid Dispersions in Rats

Bioavailability Improvement of Carbamazepine via Oral Administration of Modified-Release Amorphous Solid Dispersions in Rats

28. October 2020

The purpose of this study was to improve the bioavailability of carbamazepine (CBZ), a poorly water-soluble antiepileptic drug, via modified-release...

Development and Characterization of Pullulan-based Orally Disintegrating Films Containing Amlodipine Besylate

19. October 2020

The aim of this study was to prepare pullulan-based orally disintegrating films (ODFs) containing amlodipine besylate, an anti-hypertensive drug, by...

graphical abstract Abuse deterrent immediate release film technology (ADRIFT): A novel bilayer film technology for limiting intentional drug abuse (ADRIFT)

Abuse deterrent immediate release film technology (ADRIFT): A novel bilayer film technology for limiting intentional drug abuse

8. October 2020

Prescription opioid abuse also known as opioid epidemic has been an ever-growing problem in the United States. It has been...

De-risking excipient particle size distribution variability with automated robust mixing: Integrating quality by design and process analytical technology

8. October 2020

Particle size distribution (PSD) variability in excipients affects mixing. In response, manufacturers rely on raw material control and rigidly defined...

ATR-FTIR spectra of raw materials PVA, PHEA, and ibuprofen sodium

Influence of Polyvinyl Alcohol (PVA) on PVA-Poly-N-hydroxyethyl-aspartamide (PVA-PHEA) Microcrystalline Solid Dispersion Films

7. October 2020

This study was conducted to formulate buccal films consisting of polyvinyl alcohol (PVA) and poly-N-hydroxyethyl-aspartamide (PHEA), to improve the dissolution...

Formulation design and pharmacokinetic evaluation of docosahexaenoic acid containing self-nanoemulsifying drug delivery system for oral administration

6. October 2020

Docosahexaenoic acid is a omega-3-fatty acid which together with other long-chain omega-3-fatty acid known to have protective effect against various...

Functionalization of lipid-based formulations for oral delivery of insulin

4. October 2020

Insulin is a potent therapeutic molecule used for the treatment of diabetes mellitus type I and late-stage type II. Insulin...

Oral Excipients