Oral care product formulations, properties and challenges

19. January 2021

This review explores the physical, chemical and structural properties of key components of oral care products, whilst looking at the...

differen capsules and tablets from BIOGRUND

Using natural alternative excipients for tableting and capsule filling

15. January 2021

A large number of dietary supplements are available in solid oral dosage forms. Vitamin and mineral supplements can be easily...

graphical abstract of Development and statistical optimization of alginate-Neusilin US2 micro-composite beads to elicit gastric stability and sustained action of hesperidin

Development and statistical optimization of alginate-Neusilin US2 micro-composite beads to elicit gastric stability and sustained action of hesperidin

12. January 2021

The Alginate-Neusilin US2 micro-composite (MC) beads were fabricated and optimized for oral delivery of hesperidin (HES). A 32 full factorial design...

Better Medicines for Older Patients: Considerations between Patient Characteristics and Solid Oral Dosage Form Designs to Improve Swallowing Experience

3. January 2021

Oral drug administration provided as solid oral dosage forms (SODF) remains the major route of drug therapy in primary and...

Investigation of hydroxypropyl-β-cyclodextrin inclusion complexation of two poorly soluble model drugs and their taste-sensation – Effect of electrolytes, freeze-drying and incorporation into oral film formulations

22. December 2020

The goal for any formulation design of poorly soluble drugs is to increase the solubility. However, increased solubility is a...

Lipid-based formulations: A winning strategy for oral bioavailability enhancement

15. December 2020

The key to lipid-based formulation success relies in the right selection of the lipid excipients to develop an optimized formulation,...

Four scenarios of danazol incorporation into the cell membrane considered in the study: (a) as a free monomer or a small amorphous aggregate, (b) as a nanocrystal, (c) shuttled at the interface of the bile micelle and (d) fused as a part of a micelle.

Molecular Dynamics Simulations Reveal Membrane Interactions for Poorly Water-Soluble Drugs: Impact of Bile Solubilization and Drug Aggregation

30. November 2020

Molecular transport mechanisms of poorly soluble hydrophobic drug compounds to lipid membranes were investigated using molecular dynamics (MD) simulations. The...

Raman monitoring of semi-continuously manufactured orodispersible films for individualized dosing

23. November 2020

Orodispersible films are promising oral dosage forms for special populations. To enable continuous manufacturing of orodispersible films, monitoring of the...

graph Elongation at Break as Function of the Talc Content and Process-Parameter-Chart of the Kollicoat® Protect Based Protective Coating

Comparing Different Moisture Protective Instant Release Coatings for Solid Oral Dosage Forms

23. November 2020

Introduction: Drug stability and shelf life are main targets of current pharmaceutical development as many active ingredients are highly moisture...

graphical abstract of The Influence of Solidification on the in vitro Solubilisation of Blonanserin Loaded Supersaturated Lipid-Based Oral Formulations

The Influence of Solidification on the in vitro Solubilisation of Blonanserin Loaded Supersaturated Lipid-Based Oral Formulations

21. November 2020

Supersaturated silica-lipid hybrids have previously demonstrated improved in vitro solubilisation and in vivo oral bioavailability of poorly water-soluble drugs, however were only fabricated using...

Oral Excipients