Oral Excipients

Although oral drug delivery is preferred by patients, it is not possible for proteins because the gastrointestinal tract is not...

Gene therapy with RNA and pDNA-based drugs is limited by poor enzymatic stability and poor cellular permeation. The delivery of...

Andrographolide (AG), a major diterpene lactone isolated from Andrographis paniculata (Burm. f.) Nees (Acanthaceae), possesses a wide spectrum of biological...

The objective of this study was to investigate the application of the physically modified rice starch (MRS) produced by alcoholic-alkaline...

The emerging field of precision medicine is rapidly growing, fostered by the advances in genome mapping and molecular diagnosis. In...

Repurposing drugs such as the FDA-approved niclosamide is a highly efficient way to leverage drugs with known safety profiles to...

In this study, we developed ticagrelor-dispersed nanosuspension (TCG-NSP) to enhance the dissolution and oral bioavailability of ticagrelor (TCG) through a...

An end-to-end continuous pharmaceutical manufacturing process was developed for the production of conventional direct compressed tablets on a proof-of-concept level...

This work identifies the cause of sticking of granules in an industrial process of tableting. Retrospective multivariate statistical analysis of...

The oral bioavailability of therapeutic proteins is limited by the gastrointestinal barriers. Encapsulation of labile proteins into nanoparticles is a...