Pharma Excipients
Cellulose Esters
The rise of independent excipients
The pressure to innovate faster than their competitors has drug formulators exploring new ways to optimise manufacturing processes
Article in manufacturingchemist.com
Continuous manufacturing, for example, has evolved at a relatively fast pace, leaving drug manufacturers feeling equally challenged…
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Review Oral Modied Release Multiple-Unit Particulate Systems: Compressed Pellets, Microparticles and…
Oral modied-release multiparticulate dosage forms, which are also referred to as oral multiple-unit particulate systems, are becoming increasingly popular for oral drug delivery applications. The compaction of polymer-coated multiparticulates into tablets to produce a sustained-release dosage form…
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Physical and rheological properties of xanthan gum agglomerated in fluidized bed: Effect of HPMC as…
Physical and rheological properties of agglomerated xanthan gum (XG), commonly used as a food thickener for the management of the patients with dysphagia (swallowing difficulty), were investigated at different concentrations (0, 2, 4, and 6% w/w) of hydroxypropyl methylcellulose (HPMC) as a binder…
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FORMULATION OF SNAIL SLIME (Achatina fulica) ANTI-ACNE EMULGEL USING TWEEN 80-SPAN 80 AS EMULSIFYING…
ABSTRACT
Acne is the condition of abnormal skin which is indicated by inflammation cause by the bacterial infection of Propionibacterium acnes. The natural one which can be used for the medical treatment of acne is the snail mucus (Achatina fulica). The achasin protein of it has antibacterial…
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Impact of polymers on the aggregation of wet-milled itraconazole particles and their dissolution…
We explore the impact of various polymers and their molecular weight on the stabilization of wet-milled suspensions of itraconazole (ITZ), a poorly soluble drug, and its dissolution from spray-dried suspensions. To this end, ITZ suspensions with SSL, SL, and L grades of hydroxypropyl cellulose (HPC)…
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Effect of Binder Attributes on Granule Growth and Densification
The rate and extent of granule growth and densification during high-shear wet granulation (HSWG) depends on a variety of formulation and process variables, including material attributes of critical formulation excipients, such as binders. The effects of known binder attributes to the rate and extent…
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3D printed drug products: Non-destructive dose verification using a rapid point-and-shoot approach
08. August 2018
Three-dimensional printing (3DP) has the potential to cause a paradigm shift in the manufacture of pharmaceuticals, enabling personalised medicines to be produced on-demand. To facilitate integration into healthcare, non-destructive characterisation…
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