HPC - hydroxypropyl cellulose

Abstract Background: Hot-melt extrusion (HME) is a promising technology for the manufacturing of drug products; however, its application is limited by...

Abstract This study aimed to develop strategies to prevent accelerated drug release (alcohol-induced dose dumping) from modified-release matrix tablets in...

Abstract Background: Fused deposition modeling (FDM) is one of the most well-known and often published methods for 3D-printed drug delivery systems....

Abstract The design of free-flowing lyophilized powders by spray-freeze-drying (SFD) enables novel therapeutic applications, including nasal administration. In this study,...

This poster has been presented at the 15th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, which took place in...

Abstract Supersaturation is a widely employed strategy to improve the oral bioavailability of poorly soluble drugs, but its application is...

Abstract Poor tablet hardness and drug re-crystallization are two common challenges of amorphous solid dispersion (ASD) formulations prepared with hot-melt...

Abstract Background: Buccal administration offers direct access to systemic circulation, improving drug bioavailability when compared with the conventional oral route....

We previously demonstrated the use of near-infrared (NIR) imaging to evaluate differences in disintegration for various capsule formulations after oral...

Abstract Ezetimibe is a cholesterol absorption inhibitor widely used in the treatment of dyslipidemia. However, its clinical efficacy is limited...