HPMC - Hydroxypropylmethylcellulose

Abstract Amorphous solid dispersion (ASD) is a widely adopted strategy to enhance the solubility of poorly water-soluble drugs. However, disintegration...

Abstract Poor solubility of curcumin (Cur) has greatly limited its applications. To establish Cur amorphous solid dispersions (Cur ASDs) with...

Abstract Nose-to-brain drug delivery via nasal sprays is severely limited by low olfactory deposition. In this study, we integrate machine...

Abstract Low water solubility and extensive hepatic first-pass metabolism limit oral bioavailability of Nebivolol hydrochloride (NEB), a new-generation β-blocker agent...

Abstract Hydroxypropyl methylcellulose (HPMC) is commonly used to enable controlled release (CR) of an active pharmaceutical ingredient (API) from a...

Abstract We report gastroretentive (GR) tablets optimized via a data-driven regression-based predictive modeling strategy to determine the optimal hydroxypropyl methylcellulose...

Abstract Background/Objectives: This study aims to investigate the underexplored impact of capsule type on the performances of capsule-based dry powder...

Abstract Poor aqueous solubility and thereby poor and/or variable bioavailability of drug candidates is frequently overcome by developing enabling formulations...

Abstract Pediatric drug delivery presents unique challenges due to physiological and pharmacological differences across age groups, requiring specialized formulation approaches...

Abstract Oral dosage is the most commonly used and preferred method of drug administration due to its several advantages, including...