Segmented intravaginal ring for the combination delivery of hydroxychloroquine and anti-CCR5 siRNA nanoparticles as a potential

graphical abstract of Segmented intravaginal ring for the combination delivery of hydroxychloroquine and anti-CCR5 siRNA nanoparticles as a potential strategy for preventing HIV infection

Segmented intravaginal ring for the combination delivery of hydroxychloroquine and anti-CCR5 siRNA nanoparticles as a potential strategy for preventing HIV infection

28. June 2021

Vaginal drug delivery has been shown to be a promising strategy for the prevention of sexually transmitted infections. Therapy delivered...

Wound healing process of intestinal epithelial cells (IPEC-J2) by colonization of a cell-free space within 24 hours at a dilution of 1:2.5 (= 1,600 μg/ml) for the different capsule solutions. Fixed and stained samples were photographed using an Olympus IX-50 inverted microscope with an Olympus 10x planachromate and an Olympus E-10 digital camera at 4-megapixel resolution. HPMCst = market standard HPMC capsules; HPMCpr = polyethylene glycol and carrageen free capsules.

Effects of Different Capsule Types for Oral Application of Active Substances – Investigations with Organ-Specific Cells

22. June 2021

1.1. Background: A capsule is a solid dosage form that delivers a defined dose of an active ingredient. Most capsules...

Enabling the direct compression of metformin hydrochloride through QESD crystallization

17. June 2021

Metformin hydrochloride is a drug used in the treatment of type 2 diabetes. It shows very poor flowability and agglomeration...

Development and evaluation of a composite dosage form containing desmopressin acetate for buccal administration

16. June 2021

Desmopressin acetate (DDAVP) is an oligopeptide indicated for the treatment of primary nocturnal enuresis, for example. The poor oral bioavailability...

Anti-counterfeiting tablet coding with laster technology

Anti-counterfeiting protection, personalized medicines − development of 2D identification methods using laser technology

16. June 2021

Counterfeiting of the products for healing is as old as trading, and it is difficult to quantify the magnitude of...

graphical abstract of Nanostructured micronized solid dispersion of crystalline-amorphous metronidazole embedded in amorphous polymer matrix prepared by nano spray drying

Nanostructured micronized solid dispersion of crystalline-amorphous metronidazole embedded in amorphous polymer matrix prepared by nano spray drying

15. June 2021

In this study metronidazole drug was encapsulated by hydroxypropyl methylcellulose and polyvinylpyrrolidone polymers from solutions using nano spray drying technology....

graphical abstract of Feasibility of In-line monitoring of critical coating quality attributes via OCT: Thickness, variability, film homogeneity and roughness

Feasibility of In-line monitoring of critical coating quality attributes via OCT: Thickness, variability, film homogeneity and roughness

12. June 2021

The feasibility of Optical Coherence Tomography (OCT) for in-line monitoring of pharmaceutical film coating processes has recently been demonstrated. OCT...

graphical abstract of Enabling formulations of aprepitant: in vitro and in vivo comparison of nanocrystalline, amorphous and deep eutectic solvent based formulations

Enabling formulations of aprepitant: in vitro and in vivo comparison of nanocrystalline, amorphous and deep eutectic solvent based formulations

11. June 2021

A deep eutectic solvent (DES) is a eutectic system consisting of hydrogen bond donor and acceptor has been suggested as a promising...

graphical abstract of Rheological properties of cellulosic thickeners in hydro-alcoholic media: the science behind the formulation of hand sanitizer gels

Rheological properties of cellulosic thickeners in hydro-alcoholic media: the science behind the formulation of hand sanitizer gels

8. June 2021

Cellulosic-based thickeners are commonly used in the preparation of hydro-alcoholic hand sanitisers. Yet, little is known about the behaviour of...

Pharmaceutical amorphous solid dispersion: A review of manufacturing strategies

6. June 2021

Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and bioavailability of poorly water-soluble drugs. Various approaches have been...

HPMC - Hydroxypropylmethylcellulose

Segmented intravaginal ring for the combination delivery of hydroxychloroquine and anti-CCR5 siRNA nanoparticles as a potential strategy for preventing HIV infection

Effects of Different Capsule Types for Oral Application of Active Substances – Investigations with Organ-Specific Cells

Enabling the direct compression of metformin hydrochloride through QESD crystallization

Development and evaluation of a composite dosage form containing desmopressin acetate for buccal administration

Anti-counterfeiting protection, personalized medicines − development of 2D identification methods using laser technology

Nanostructured micronized solid dispersion of crystalline-amorphous metronidazole embedded in amorphous polymer matrix prepared by nano spray drying

Feasibility of In-line monitoring of critical coating quality attributes via OCT: Thickness, variability, film homogeneity and roughness

Enabling formulations of aprepitant: in vitro and in vivo comparison of nanocrystalline, amorphous and deep eutectic solvent based formulations

Rheological properties of cellulosic thickeners in hydro-alcoholic media: the science behind the formulation of hand sanitizer gels

Pharmaceutical amorphous solid dispersion: A review of manufacturing strategies

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