Microwave-induced in situ drug amorphization using a mixture of polyethylene glycol and polyvinylpyrrolidone

25. May 2021

The use of a mixture of polyethylene glycol (PEG) and polyvinylpyrrolidone (PVP) was investigated for microwave-induced in situ amorphization of...

graphical abstract of The Effect of Process Variables and Binder Concentration on Tabletability of Metformin Hydrochloride and Acetaminophen Granules Produced by Twin Screw Melt Granulation with Different Polymeric Binders

The Effect of Process Variables and Binder Concentration on Tabletability of Metformin Hydrochloride and Acetaminophen Granules Produced by Twin Screw Melt Granulation with Different Polymeric Binders

18. May 2021

In twin screw melt granulation, granules are produced by passing mixtures of drug substances and polymeric binders through twin screw...

Combination of PAT and mechanistic modeling tools in a fully continuous powder to granule line: Rapid and deep process understanding

3. May 2021

Comprehensive understanding of an integrated continuous pharmaceutical technology was achieved in this study by a combining design of experiments and...

Comparative taste-masking evaluation of microencapsulated bitter drugs using Smartseal 30D and ReadyMix for paediatric dosage forms

28. April 2021

The taste of drug substances plays a key role in the development of paediatric formulations with suitable organoleptic properties. The...

Achieving gastroresistance without coating: Formulation of capsule shells from enteric polymers

26. April 2021

Capsules are a widely used oral dosage form due to their simplicity and ease of manufacture. They are equally popular...

Radar plot of palatability results for swallowability, taste immediately after administration, texture and taste

The Development of Minitablets for a Pediatric Dosage Form for a Combination Therapy

22. April 2021

Minitablets are an appealing option for an age-appropriate pediatric dosage form. In particular, for combination therapies where multiple active ingredients...

graphical abstract of Formulation and process strategies to minimize coat damage for compaction of coated pellets in a rotary tablet press: A mechanistic view

Formulation and process strategies to minimize coat damage for compaction of coated pellets in a rotary tablet press: A mechanistic view

15. April 2021

Compaction of multiple-unit pellet system (MUPS) tablets has been extensively studied in the past few decades but with marginal success....

Synergistic application of twin-screw granulation and selective laser sintering 3D printing for the development of pharmaceutical dosage forms with enhanced dissolution rates and physical properties

13. April 2021

This study demonstrated the first case of combining a novel continuous granulation technique with powder-bed fusion-based selective laser sintering (SLS)...

Nateglinide solid dispersion optimized formulation

Design, Development, and Evaluation of Controlled Release Tablets of Nateglinide Solid Dispersions

11. April 2021

The current study deals with formulation and evaluation of nateglinide solid dispersion (SD) incorporate into tablet formulation for controlled release...

Design and characterisation of an amorphous formulation of nifedipine for the treatment of autonomic dysreflexia

8. April 2021

Current treatment for autonomic dysreflexia (AD) involves rupturing a liquid-filled soft capsule of nifedipine to aid rapid drug release and...

Acrylic Polymers