Polylacticcoglycolic acid – PLGA

The intra-sphere and inter-sphere structural attributes of controlled release microsphere drug products can greatly impact their release profile and clinical...

Abstract The management of chronic conditions often requires patients to take daily medication for an extended duration. However, the need...

Abstract Poly(lactic-co-glycolic acid) (PLGA) microspheres are a sustained-release drug delivery system with several successful commercial products used for the treatment...

Background: To develop a first-time-novel polymeric NPs from PLGA and their coating by Chitosan (CS) of Melatonin (MT) for the enhancement...

Morin (3,5,7,2′,4′-pentahydroxyflavone; MR) is a bioactive plant polyphenol whose therapeutic efficacy is hindered by its poor biopharmaceutical properties. The purpose...

Transdermal delivery of drugs offers an interesting alternative for the administration of molecules that present certain troubles when delivered by...

Hot-melt extrusion (HME) is used for the production of solid protein formulations mainly for two reasons: increased protein stability in...

A full-thickness or hard-to-heal wound pose a significant challenge in clinical feilds. These wounds are very prone to microbial infection,...

Topical therapies for chronic skin diseases suffer from a low patient compliance due to the inconvenient treatment regimens of available...

Flavonoids are natural compounds that are attracting great interest in the biomedical field thanks to the wide spectrum of their...