Polysorbates

Abstract Lipid-based drug delivery carriers have exhibited substantial potential for promoting wound healing. Here, Phospholipon® 90H (P90H) based lipid nanoparticles...

Abstract The limited aqueous solubility of numerous active pharmaceutical ingredients (APIs) remains a major barrier to achieving optimal oral bioavailability,...

Abstract Background: Despite the growing importance of polypeptide-based drugs in clinical therapy, studies investigating the stability of their freeze-dried formulations...

Abstract Cancer remains to be one of the most life-threatening diseases with high rates of mortality and morbidity. The major...

Abstract Polysorbate 20 (PS20) and polysorbate 80 (PS80) are essential surfactants used to stabilize biopharmaceutical products, yet their highly heterogeneous...

Abstract Formulation development of protein biopharmaceuticals has become increasingly challenging due to new modalities and higher target drug substance concentrations....

Abstract Polysorbate 20 (PS20) is one of the most commonly used non-ionic surfactants in cosmetics, pharmaceuticals and food products. Considered...

Abstract Biopharmaceutical medicines represent one of the most dynamic sectors of the pharmaceutical industry, with therapeutic proteins forming the largest...

Abstract Surface adsorption of proteins in bulk drug product formulations and loss of protein structural integrity during manufacturing processes can...

Abstract Ezetimibe is a cholesterol absorption inhibitor widely used in the treatment of dyslipidemia. However, its clinical efficacy is limited...