Back to shop

Labrafil M 1944 CS

0.00

Clear
-
+

Total:

Description

A nonionic water-dispersible surfactant for lipid-based formulations to solubilize and increase oral bioavailability of poorly water-soluble APIs. Self-emulsifies in aqueous media forming a coarse dispersion, i.e., emulsion (SEDDS). Co-emulsifier in topical formulations to improve stability of emulsions.

Main functionalities: Solubilizer for poorly-soluble API and bioavailability enhancer Single excipient formulation system: self-emulsifies in aqueous fluid into emulsion – LFCS type II (SEDDS) Combine with Labrasol®ALF or Gelucire® 44/14 for LFCS Type III (SMEDDS) Co-emulsifier in topical formulations often associated with Tefose® 63 in antifungal cream Safety of use is supported by substantial toxicological data and precedence of use in approved pharmaceutical products.

Additional information

Manufacturer

Gattefosse

Quality

USP-NF/EP

Composition

Consists of mono-, di- and triglycerides and PEG-6 (MW 300) mono- and diesters of oleic (C18:1) acid

Dosage Form

Parenteral, Topical

Function

Solubilizer for poorly-soluble API and bioavailability enhancer Single excipient formulation system

Cas-No

69071-70-1

Einecs

NOT- AP-PL.

Compendial Name

APRICOT KERNEL OIL PEG-6 ESTERS, Oleoyl macrogol-6 glycerides, Oleoyl polyoxyl-6 glycerides

Documents and Links