Labrafil M 1944 CS
€0.00
Description
A nonionic water-dispersible surfactant for lipid-based formulations to solubilize and increase oral bioavailability of poorly water-soluble APIs. Self-emulsifies in aqueous media forming a coarse dispersion, i.e., emulsion (SEDDS). Co-emulsifier in topical formulations to improve stability of emulsions.
Main functionalities: Solubilizer for poorly-soluble API and bioavailability enhancer Single excipient formulation system: self-emulsifies in aqueous fluid into emulsion – LFCS type II (SEDDS) Combine with Labrasol®ALF or Gelucire® 44/14 for LFCS Type III (SMEDDS) Co-emulsifier in topical formulations often associated with Tefose® 63 in antifungal cream Safety of use is supported by substantial toxicological data and precedence of use in approved pharmaceutical products.
Additional information
| Manufacturer | Gattefosse |
|---|---|
| Quality | USP-NF/EP |
| Composition | Consists of mono-, di- and triglycerides and PEG-6 (MW 300) mono- and diesters of oleic (C18:1) acid |
| Dosage Form | Parenteral, Topical |
| Function | Solubilizer for poorly-soluble API and bioavailability enhancer Single excipient formulation system |
| Cas-No | 69071-70-1 |
| Einecs | NOT- AP-PL. |
| Compendial Name | APRICOT KERNEL OIL PEG-6 ESTERS, Oleoyl macrogol-6 glycerides, Oleoyl polyoxyl-6 glycerides |
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