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Labrafil M 2125 CS

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Description

A liquid nonionic water-dispersible surfactant for lipid-based formulations to solubilize and increase oral bioavailability of poorly water-soluble APIs. Self-emulsifies in aqueous media forming a coarse dispersion, i.e., emulsion (SEDDS).

Main functionalities: Solubilizer for poorly-soluble APIs and bioavailability enhancer. Single excipient formulation system: self-emulsifies in aqueous fluid into emulsion—LFCS Type II (SEDDS). Combine with Labrasol® ALF or Gelucire® 44/14 for LFCS Type III (SMEDDS). Safety of use is inferred by substantial toxicological data and precedence of use in approved pharmaceutical products.

Additional information

Manufacturer

Gattefosse

Quality

USP-NF/EP

Composition

Consists of mono-, di- and triglycerides and PEG-6 (MW 300) mono- and diesters of linoleic (C18:2) acid

Dosage Form

emulgel, microemulsion and foam), Oral, Self-emulsifying lipid formulation for oral applications. Soft/hard gelatin capsule filling, vials.

Function

emulsion (SEDDS). Co-emulsifier in topic, i.e.

Compendial Name

CORN OIL PEG-6 ESTERS, Linoleoyl Macrogol-6 glycerides, Linoleoyl Polyoxyl-6 glycerides

Cas-No

61789-25-1

Einecs

NOT- AP-PL.

Documents and Links

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