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Abstract Roller compaction/dry granulation (RC/DG) is a key process in pharmaceutical manufacturing for improving powder flowability, density, and segregation resistance....
Abstract We propose a novel approach for predicting the solid fraction after roller compaction processes. It is crucial to predict...
Abstract Process Analytical Technology (PAT) plays a crucial role in the design of today’s manufacturing lines as continuous manufacturing becomes...
Abstract Roller compaction is a key unit operation in a dry granulation line for pharmaceutical tablet manufacturing. During product development,...
Abstract Ribbon porosity is a critical parameter to monitor in the roller compaction process. In this study, six techniques for...
The challenges of developing good quality low dose minitablets was assessed by systematically studying the effects of ibuprofen (IBU, a...
Abstract Roller compaction is a widely used continuous dry granulation process in the food and pharmaceutical industries. The flow and...
Principal component analysis (PCA) and partial least squares regression (PLS) were combined in this study to identify key material descriptors...
Abstract This research investigates the modeling of the pharmaceutical roller compaction process, focusing on the application of the Johanson model...
Abstract Roller compaction is gaining importance in the pharmaceutical industry. This study evaluates the impact of ribbon milling conditions on...
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