Solid Dispersion

Abstract The liquid and solid formulations of self-nano-emulsifying drug delivery systems (SNEDDS) have garnered significant attention in the pharmaceutical field...

Abstract Background: Solid dispersions (SDs) of etodolac (ETD), a poorly water-soluble drug model, were developed to enhance its solubility and dissolution...

Abstract PROTACs are an emerging class of beyond-rule-of-5 molecular drugs currently under clinical investigation for the treatment of malignant diseases...

Abstract The presence of N-nitrosamine impurities and nitrosamine drug substance-related impurities (NDSRIs) in medicines poses a significant challenge not only for...

Abstract To prevent contamination by nitrosamine drug substance-related impurities (NDSRIs) in solid dosage forms, the modeling of drug nitrosation reactions...

Abstract Polymeric amorphous solid dispersions (ASDs) are frequently used to improve solubility and oral bioavailability of poorly water-soluble drugs. The...

Abstract Ezetimibe is a cholesterol absorption inhibitor widely used in the treatment of dyslipidemia. However, its clinical efficacy is limited...

Abstract Amorphous solid dispersions (ASDs) represent a promising formulation strategy for improving the solubility and bioavailability of poorly water-soluble drugs,...

Abstract Lornoxicam, a potent nonsteroidal anti-inflammatory drug (NSAID), suffers from poor aqueous solubility, leading to limited dissolution and variable bioavailability....

This poster was presented by Gattefossé at CRS 2025, the Annual Meeting and Exposition conference 2025 in Philadelphia, PA: Introduction...