Solid Dispersion

Precision 3D Printing in Pharmaceutical Sciences: A Transformative Shift in Drug Manufacturing and Delivery Systems See the new book, edited...

Precision 3D Printing in Pharmaceutical Sciences: A Transformative Shift in Drug Manufacturing and Delivery Systems See the new book, edited...

Abstract Amorphous solid dispersions (ASD) are an effective strategy to enhance the solubility of poorly water-soluble drugs. Hot melt extrusion...

Abstract Pramipexole dihydrochloride (PPX) is a Biopharmaceutical Classification System (BCS) Class I drug with a short half-life, and its aqueous...

Abstract The liquid and solid formulations of self-nano-emulsifying drug delivery systems (SNEDDS) have garnered significant attention in the pharmaceutical field...

Abstract Background: Solid dispersions (SDs) of etodolac (ETD), a poorly water-soluble drug model, were developed to enhance its solubility and dissolution...

Abstract PROTACs are an emerging class of beyond-rule-of-5 molecular drugs currently under clinical investigation for the treatment of malignant diseases...

Abstract The presence of N-nitrosamine impurities and nitrosamine drug substance-related impurities (NDSRIs) in medicines poses a significant challenge not only for...

Abstract To prevent contamination by nitrosamine drug substance-related impurities (NDSRIs) in solid dosage forms, the modeling of drug nitrosation reactions...

Abstract Polymeric amorphous solid dispersions (ASDs) are frequently used to improve solubility and oral bioavailability of poorly water-soluble drugs. The...