Solubility Enhancement

  Lipid excipients offer a unique combination of benefits Poor solubility, poor permeability, and pre-systemic elimination are factors that can...

Abstract Background/Objectives: Dihydroquercetin (DHQ), also known as taxifolin, is a natural flavonoid which has anti-inflammatory and wound-healing biological effects. One...

Abstract Lipid-based formulations (LBFs) play a crucial role in enhancing the oral bioavailability of poorly water-soluble drugs by leveraging lipid...

Abstract Manufacturing co-processed pharmaceutical excipients is a great innovation in drug delivery, with improved compressibility, flowability, disintegration, and reduced moisture...

Abstract Amorphous solid dispersions (ASD) are an effective strategy to enhance the solubility of poorly water-soluble drugs. Hot melt extrusion...

Drug Delivery and Biomedical Applications of Porous Silicon-Based Nanocarriers See the new book, edited by Rajendra Awasthi, Santosh Kumar Singh,...

Abstract Background: Solid dispersions (SDs) of etodolac (ETD), a poorly water-soluble drug model, were developed to enhance its solubility and dissolution...

Abstract Famotidine suffers from low oral bioavailability due to poor aqueous solubility, short half-life, and limited gastric retention. This study...

Abstract The current work uses liquisolid (LS) technology to increase the absorption efficiency and dissolution rate of the weakly water-soluble...

Abstract PROTACs are an emerging class of beyond-rule-of-5 molecular drugs currently under clinical investigation for the treatment of malignant diseases...