Solubility Enhancement

Abstract Famotidine suffers from low oral bioavailability due to poor aqueous solubility, short half-life, and limited gastric retention. This study...

Abstract The current work uses liquisolid (LS) technology to increase the absorption efficiency and dissolution rate of the weakly water-soluble...

Abstract PROTACs are an emerging class of beyond-rule-of-5 molecular drugs currently under clinical investigation for the treatment of malignant diseases...

Abstract Aqueous solubility is a crucial physicochemical property influencing drug absorption and bioavailability. Current solubility assays, whether assessing thermodynamic or...

Dr. Paul Lohmann presents two focus areas for their CPhI Frankfurt booth: Mineral Salts as APIs  The Dr. Paul Lohmann...

Abstract Ezetimibe is a cholesterol absorption inhibitor widely used in the treatment of dyslipidemia. However, its clinical efficacy is limited...

PRESS RELEASE October 8, 2025, Asahi Kasei Corp. - Asahi Kasei, a trusted provider in healthcare materials and technology, announced...

Abstract Lornoxicam, a potent nonsteroidal anti-inflammatory drug (NSAID), suffers from poor aqueous solubility, leading to limited dissolution and variable bioavailability....

Abstract Uveitis is an ocular inflammatory condition that can be infectious or non-infectious, affecting various ocular structures. Corticosteroids and immunomodulators...

Abstract Pulmonary delivery can deliver cannabidiol (CBD) with high bioavailability and fast onset of action. One formulation obstacle is the...