Solubility Enhancement

Thesis by Jeremiah Kelleher, School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, The University of Dublin The thesis has focused on...

The term “multicomponent solid dispersion” is widely used in recent literature to describe solid formulations consisting of a special excipient's...

Abiraterone acetate is a potent drug used for the treatment of metastatic castration resistant prostate cancer. However, currently marketed product...

Repurposing drugs such as the FDA-approved niclosamide is a highly efficient way to leverage drugs with known safety profiles to...

A well-designed drug delivery platform improves the pharmacological properties of therapeutics. Here, we report a biodegradable interpenetrating polymer network (IPN)...

Rutin is one of the most important flavonoids with poor bioavailability. This work aimed at addressing the issue of poor...

Repurposing drugs such as the FDA-approved niclosamide is a highly efficient way to leverage drugs with known safety profiles to...

Although solid dispersions have been reported as an efficient drug delivery system, the design of specific dosage forms for pharmaceutical...

Purpose Abiraterone acetate (AbA) is a poorly water-soluble drug with an oral bioavailability of <10% and a significant pharmaceutical food...

Although flurbiprofen (FB), as one of non-steroidal anti-inflammatory drugs, has various pharmacological applications, it shows low dermal bioavailability due to...