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Spray drying biologics and small-molecule drugs can increase their thermal stability relative to liquid dosage forms and allow for widespread...
Two enveloped viral vectors, vesicular stomatitis virus and influenza virus, and a non-enveloped viral vector, human adenovirus type 5, were...
Mannitol is classified as a sugar alcohol and is derived from a sugar (mannose) by reduction. Other widely known polyols...
The aim of this study was to identify critical steps to protein stability during spray drying using two different nozzle...
26. March 2018 Spray-dried protein formulations commonly require stabilising excipients to prevent protein degradation during processing and storage, and trehalose...
08. October 2017 Increasing knowledge about the human microbiome has led to a growing awareness of the potential of applying...
17. August 2017 For the development of this excipient for direct compression no chemical modification was applied. The enhanced functionality...
10. May 2017 Abstract Colloidal drug delivery systems often face physical and chemical instability as well as challenges with directed...
31. March 2017 The majority of today’s new chemical entities are poorly water-soluble. One widely used means of overcoming that...
03. January 2017 Abstract Efavirenz (EFV), a non-nucleoside reverse transcriptase inhibitor (NNRTI), is part of first-line therapy for the treatment...
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