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Background and objective: Dry powder inhalation provide many promising features for drug delivery to the pulmonary system, such as localization...
Purpose: Novel tablet coating approaches include the development of continuous coating technologies. This requires a high level of automation to...
Localized aerosol delivery of gene therapies is a promising treatment of severe pulmonary diseases including lung cancer, cystic fibrosis, COPD...
Spray drying biologics and small-molecule drugs can increase their thermal stability relative to liquid dosage forms and allow for widespread...
Two enveloped viral vectors, vesicular stomatitis virus and influenza virus, and a non-enveloped viral vector, human adenovirus type 5, were...
Mannitol is classified as a sugar alcohol and is derived from a sugar (mannose) by reduction. Other widely known polyols...
The aim of this study was to identify critical steps to protein stability during spray drying using two different nozzle...
26. March 2018 Spray-dried protein formulations commonly require stabilising excipients to prevent protein degradation during processing and storage, and trehalose...
08. October 2017 Increasing knowledge about the human microbiome has led to a growing awareness of the potential of applying...
17. August 2017 For the development of this excipient for direct compression no chemical modification was applied. The enhanced functionality...
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